Acts regarding reasons for genome in sperm cells being packed poorly, resulting in the possibility of DNA fragmentation: THE PHYSICIAN CAN EXAMINE AND TREAT YOU FOR THE FOLLOWING: Leukocytospermia: High white blood cell count in the sperm. Diabetes: Diabetes or pre-diabetes (hyperinsulinaemia). Varicocele: Abnormal enlargement of the veins from the testicles. WHAT CAN YOU DO? Temperature: The normal temperature of the scrotum is 33.3ºC and can be increased for many reasons. Avoid hot baths or spa. Avoid tight underwear and pants. Place the portable computer on the table instead of on your lap. Turn down the heat in the car seat. High fever, for example in connection with flu, can also cause problems. Smoking: Quit smoking, if you can. Overweight: Maintain a healthy diet. Weight loss is a good idea if your BMI is above 25. Changes in the diet can also reduce hyperinsulinaemia and result in better packing of the genome in the sperm cells. Medicine: Many medicines cause problems. If you are taking medicine, you should inform your fertility specialist of this. Cholesterol reducing medicine, stomach ulcer remedies and antidepressants have a well-known negative effect. Regarding many types of medicine, we currently do not know whether they affect the packing of the genome in the sperm cells. Mobile phone: Radiation from mobile phones causes problems. When you have it on you, it should be in your breast pocket and not your trouser pocket. WHAT IS DIFFICULT TO CHANGE? Age: Already having had children, unfortunately, provides no guarantees that problems won’t come about in future. The environment: Air pollution, pesticides plus various chemicals can cause problems. Always adhere to safety precautions when dealing with chemicals and pesticides. Remember to rinse vegetables and wipe off fruit. Recently, there has been an increased emphasis on the evaluation of sperm quality. Much of this has been due to a growing realisation that a sperm or semen test is actually of limited value. Sperm, in essence, acts as little more than vehicles by which DNA is carried from the male to the female egg. Only very few make it to their goal, and along the way, a potentially damaging process is undertaken, where the protein blocks designed to protect the sperm can very often fail, leaving DNA susceptible to damage and at risk of becoming fragmented. Best Fertility Care Centre, Maternal & amp; Child Health Care Centre , Advanced Fertility Care Centre , Ashwini Hospital & amp; Fertility Centre Moondrumavadi K.Pudur Madurai-07 , Low Cost IVF & amp; ICSI Centre, Normal Vaginal Delivery Rs. 35000/- (Including Medicines) LSCS Rs.50000/-(including medicines)